mxODBC  
   A DB-API 2.0 compliant ODBC Interface for Python. [Commercial, free for non-commercial use]
   http://www.lemburg.com/files/python/mxODBC.html

ODBC Module  
   Offers sample source codes of open database connection.
   http://www.python.org/windows/win32/odbc.html

PyGreSQL  
   PostgreSQL module for Python. [Open Source, BSD-like]
   http://www.druid.net/pygresql/

PoPy  
   A PostgreSQL driver for Python. [Open Source, GPL]
   http://popy.sourceforge.net/

kinterbasdb  
   Python module for interfacing Interbase databases. [Open Source, BSD-like]
   http://kinterbasdb.sourceforge.net/

DCOracle  
   Python DB-API interface to Oracle 7 and 8 databases. [Open Source, BSD-like]
   http://www.zope.org/Products/DCOracle

zxJDBC  
   Database connectivity in Jython (Python on the Java platform). [Open Source, Python license]
   http://www.ziclix.com/zxjdbc/

Sybase module for Python  
   A Python interface to the Sybase relational database system. [Open Source, BSD-like]
   http://www.object-craft.com.au/projects/sybase/

MetaKit for Python  
   A Python interface to MetaKit. MetaKit is an embeddable database which runs on Unix, Windows, Macintosh, and other platforms. [Open-Source, MIT]
   http://www.equi4.com/metakit/python.html

pyBSDdb  
   Python bindings for BerkeleyDB 3.x embeddable database. [Open Source, BSD-like]
   http://pybsddb.sourceforge.net/

Ingres interface  
   A Python database API 2.0 conforming CA Ingres module.
   http://www.informatik.uni-rostock.de/~hme/software/

SQLDict Module  
   A dictionary-style interface around any DB API-compatible database. [Open Source, BSD-like]
   http://dustman.net/andy/python/SQLDict

SAP DB  
   An interface to the SAP DB database. [Open Source, LGPL]
   http://www.sapdb.org/sap_db_program.htm

mxBeeBase  
   On-disk B+Tree Based Database Kit. [Open Source]
   http://www.lemburg.com/files/python/mxBeeBase.html

DCOracle2  
   A Python DB API 2.0 adapter for Oracle 8. [Open Source, ZPL]
   http://www.zope.org/Members/matt/dco2

Python Database Row Module  
   This Python 2.2 module defines light-weight objects which allow very flexible access to a fixed number of positional and named attributes via several interfaces. [Open Source, BSD-like]
   http://opensource.theopalgroup.com/

PySQLite  
   A Python interface using the SQLite embedded relational database engine that will conform to the Python Database API Specification 2.0. [Open Source, Python license]
   http://pysqlite.sourceforge.net/

pyPgSQL  
   A Python DB-API 2.0 compliant interface to a PostgreSQL (v7.0 and later) database. [Open Source, BSD-like]
   http://pypgsql.sourceforge.net/

DMtools  
   A data mining toolbox with caching of database queries and parallelism within a collection of independent queries. [Open Source, GPL]
   http://csl.anu.edu.au/ml/dm/dm_software.html

cx_Oracle  
   Oracle 8i interface developed by Computronix. [Open Source, BSD-like]
   http://www.computronix.com/utilities.shtml

MySQLdb  
   Python interface to MySQL databases. [Open Source, Python License/GPL]
   http://sourceforge.net/projects/mysql-python/

ADODBAPI  
   A DB-API 2.0 module for accessing data sources via Micrsosoft ADO. [Open Source, LGPL]
   http://adodbapi.sourceforge.net/

Python SQL Database Access System  
   A simple and consistent programming interface to SQL databases, in Python. [Open source, Python Software Foundation License]
   http://sourceforge.net/projects/pysqldb/

SQL Relay  
   Persistent database connection pooling, proxying and load balancing system for Unix with a Python API. [Open Source]
   http://sourceforge.net/projects/sqlrelay/

GV Interbase Database Adapter  
   A database adapter for the Interbase relational database.
   http://www.zope.org/Members/bkc/gvibDA

ZODB  
   The Z Object Database, or the ZODB for short, is a powerful and easy-to-use object persistence system for Python. [Open Source, ZPL]
   http://zope.org/Wikis/ZODB/FrontPage

PDO  
   Python Database Objects provides a convenient Object Oriented API for database access in Python. PDO supports multiple RDBMS with the same API, and provides features not found in the DB-API spec, such as column access by name. [OPen source, BSD style lic
   http://pdo.neurokode.com/

pSQL  
   A wrapper above MySQLdb which renders MySQL databases as very comfortable pythonic objects.
   http://software.fionet.com/pSQL/

ZODB-Tutorial.py  
   A number of hands-on code example how to use the ZODB.
   http://www.h7.dion.ne.jp/~harm/ZODB-Tutorial.py

Metakit for Python (Mk4py)  
   A lower-level API for the Metakit C++ core extension, and uses SCXX by Gordon McMillan as C++ glue interface. [X/MIT-style and commercial licenses]
   http://www.equi4.com/metakit.html

psycopg  
   A PostgreSQL database adapter for Python. [Open Source, GPL]
   http://initd.org/projects/psycopg1

SnakeDb  
   An easy database API that is a wrapper around other Python database modules (like Gadfly and MySQLdb). [Open source, GPL]
   http://sourceforge.net/projects/snakedb/